Top Pharmaceutical Company of Bangladesh: 2011

		Tk (Crore)	Share	Growth %
Rank	Total Market	7,186	100.00	24.30
1	SQUARE	1,378	19.18	23.54
2	INCEPTA PHARMA	650	9.05	32.17
3	BEXIMCO	620	8.62	40.33
4	OPSONIN PHARMA	355	4.94	26.09
5	ESKAYEF	348	4.84	24.82
6	RENATA	340	4.73	29.63
7	ACME	319	4.44	17.34
8	A.C.I.	293	4.08	18.81
9	ARISTOPHARMA	286	3.99	21.63
10	DRUG INTERNATIONAL	270	3.75	18.18
11	SANOFI AVENTIS	185	2.57	8.77
12	GLAXOSMITHKLINE	140	1.95	10.84
13	ORION PHARMA LTD.	140	1.94	31.47
14	NOVO NORDISK	128	1.79	27.72
15	HEALTHCARE PHARMA	126	1.75	33.20
16	GENERAL	117	1.63	19.25
17	SANDOZ	109	1.51	12.25
18	POPULAR PHARMA	94	1.31	54.53
19	NOVARTIS	94	1.30	46.01
20	IBN SINA	93	1.29	19.49
21	NUVISTA PHARMA	83	1.16	37.93
22	UNIMED &UNIHEALTH	68	0.94	22.80
23	SUN PHARMA	60	0.84	54.63
24	GLOBE	57	0.80	24.72
25	BIO PHARMA	56	0.78	21.07
26	ROCHE	50	0.70	42.24
27	RADIANT PHARMA	41	0.57	71.73
28	PACIFIC	41	0.57	18.46
29	JAYSON	38	0.52	10.97
30	BEACON PHARMA	37	0.52	18.11
31	SMC	33	0.46	-1.25
32	ORION INFUSION	32	0.45	12.26
33	OPSO SALINE	30	0.42	1.85
34	KEMIKO PHARMA LTD.	29	0.41	4.68
35	NAVANA	29	0.40	-1.94
36	DELTA PHARMA	27	0.38	53.11
37	SERVIER	27	0.37	23.61
38	SOMATEC	23	0.33	4.37
39	RANGS PHARMA	22	0.31	-3.85
40	LIBRA	21	0.30	-4.70
41	ALCO PHARMA	21	0.29	5.44
42	APEX PHARMA	20	0.28	38.84
43	PHARMADESH	19	0.26	80.09
44	SILVA PHARMA	14	0.19	-1.21
45	MEDIMPEX	12	0.17	-50.53
46	EDRUC	11	0.15	-19.17
47	ZISKA	10	0.15	-0.71
48	WHITE HORSE PHARMA	10	0.14	81.65
49	RAK PHARMA LTD.	8	0.12	441.79
50	ASIATIC	8	0.12	65.29
	* Others *	162	2.24	0.00

Data Source: Bangladesh Pharmaceutical Index' 1st Q, 2011

Top 20 Pharmaceutical Company of Bangladesh : 2010

Rank		SALE (Tk Cr.)	Share (%)	Growth (%)
	Total Market	6,457.22		24.58
1	SQUARE	1,238.65	19.18	21.28
2	INCEPTA	573.63	8.88	37.79
3	BEXIMCO	528.65	8.19	34.50
4	OPSONIN	316.62	4.90	31.17
5	ESKAYEF	316.49	4.90	29.81
6	RENATA	306.23	4.74	36.98
7	ACME	293.93	4.55	13.64
8	A.C.I	277.16	4.29	21.16
9	ARISTO	260.77	4.04	24.06
10	Drug Int	249.85	3.87	24.48
11	AVENTIS	179.36	2.78	11.58
12	GLAXO	131.61	2.04	7.96
13	ORION LAB.	124.76	1.93	38.69
14	NOVO NORDISK	116.69	1.81	56.39
15	HEALTHCARE	108.30	1.68	30.74
16	GENERAL	105.47	1.63	12.68
17	SANDOZ	90.59	1.40	-3.78
18	IBN SINA	89.60	1.39	30.80
19	POPULAR	72.77	1.13	47.52
20	NOVARTIS	72.60	1.12	22.96

Data Source: Bangladesh Pharmaceutical Index (3Q, 2010)

Why Chewable Antacid is Better in heartburn?

Chewable antacid is more effective in preventing heartburn than swallowing an antacid, because antacids are primarily active in esophageal lumen, rather than neutralization of intragastric contents. When a tablet is swallowed it passes through the stomach too fast to neutralize the acid and when a tablet chewed, the antacid is ready to work as soon as it reaches the stomach.

Novelta: A Novel Antacid

Brand name : Novelta

Generic name : Magaldrate USP + Simethicone USP

Therapeutic class : Antacid

Dosage form : Chewable Tablet

Strength : (Magaldrate USP 480 mg + Simethicone USP 20 mg)

Pack size : 10x10’s

MRP/Box : Tk. 200 (Tk. 2.00/Tablet)

Indications

Hyperacidity, Gastric & Duodenal ulcer, Gastritis, Heartburn, Dyspepsia, Gastroesophageal reflux. Also indicated for the relief of Flatulence, Abdominal distention and Windy colic.

Mechanism of Action

Magaldrate is a sulfate containing hydroxymagnesium aluminate complex, hydrotalcite like lattice layer structure and a discrete chemical entity rather than a physical mixture of Al (OH)₃ & Mg(OH)₂. The approximate formula of Magaldrate is Al₅Mg₁₀(OH)₃₁(SO₄)₂.xH₂O.

Magaldrate

• After ingestion of Novelta chewable tablet

• The hydroxymagnesium is relatively rapidly converted to Magnesium ion

• The negative charged layer situated between the positive charged layers that soaks up H⁺ ions

• Rapid onset of action occurs

• Aluminate converted to hydrated aluminium hydroxide

• Reacts more slowly to give a sustained antacid effect

• Prolonged acid neutralization occurs

  Simethicone

• Acts in the stomach and intestine

• Decreases the surface tension of gas bubbles

• Enabling them to coalesce
• Gas is freed and eliminated more easily
• By belching or passing flatus

Dosage and Administration

1-4 tablets of Novelta chewable tablet, 20 minutes to 1 hour after meals and at bedtime, or as directed by physician.

To See Documentary on Novelta Please follow these link: Novelta: A Novel Antacid

Azithromycin in Acne treatment

Acne is a common inflamatory disorder of the skin. It is a multifactorial disease caused by follicular hyperkeratinization, infection with Propionibacterium acnes, increase sebum production and information.

Dose for Acne: Azithromycin (Azalid) 500 mg tablet, 3 days per week for 8-12 weeks.

Anxiety Symptoms, Cause and Treatment Option

What is Anxiety

Anxiety disorders are serious mental illness that involves intense feelings of fear, tension, worry often associated with specific situation, events or objects

Symptoms of anxiety

• Palpitation

• Tachycardia

• Sweating

• Tremor

• Hypertension

• Restlessness

• Agitation

• GIT disorders

• Sleep disturbance.