Monday, April 25, 2011

Top 20 Pharmaceutical Company of Bangladesh : 2010

Rank

SALE

(Tk Cr.)

Share (%)

Growth (%)

Total Market

6,457.22

24.58

1

SQUARE

1,238.65

19.18

21.28

2

INCEPTA

573.63

8.88

37.79

3

BEXIMCO

528.65

8.19

34.50

4

OPSONIN

316.62

4.90

31.17

5

ESKAYEF

316.49

4.90

29.81

6

RENATA

306.23

4.74

36.98

7

ACME

293.93

4.55

13.64

8

A.C.I

277.16

4.29

21.16

9

ARISTO

260.77

4.04

24.06

10

Drug Int

249.85

3.87

24.48

11

AVENTIS

179.36

2.78

11.58

12

GLAXO

131.61

2.04

7.96

13

ORION LAB.

124.76

1.93

38.69

14

NOVO NORDISK

116.69

1.81

56.39

15

HEALTHCARE

108.30

1.68

30.74

16

GENERAL

105.47

1.63

12.68

17

SANDOZ

90.59

1.40

-3.78

18

IBN SINA

89.60

1.39

30.80

19

POPULAR

72.77

1.13

47.52

20

NOVARTIS

72.60

1.12

22.96


Data Source: Bangladesh Pharmaceutical Index (3Q, 2010)

Why Chewable Antacid is Better in heartburn?

Chewable antacid is more effective in preventing heartburn than swallowing an antacid, because antacids are primarily active in esophageal lumen, rather than neutralization of intragastric contents. When a tablet is swallowed it passes through the stomach too fast to neutralize the acid and when a tablet chewed, the antacid is ready to work as soon as it reaches the stomach.

Sunday, April 24, 2011

Novelta: A Novel Antacid



Brand name : Novelta

Generic name : Magaldrate USP + Simethicone USP

Therapeutic class : Antacid

Dosage form : Chewable Tablet

Strength : (Magaldrate USP 480 mg + Simethicone USP 20 mg)

Pack size : 10x10’s

MRP/Box : Tk. 200 (Tk. 2.00/Tablet)


Indications

Hyperacidity, Gastric & Duodenal ulcer, Gastritis, Heartburn, Dyspepsia, Gastroesophageal reflux. Also indicated for the relief of Flatulence, Abdominal distention and Windy colic.

Mechanism of Action

Magaldrate is a sulfate containing hydroxymagnesium aluminate complex, hydrotalcite like lattice layer structure and a discrete chemical entity rather than a physical mixture of Al (OH)3 & Mg(OH)2. The approximate formula of Magaldrate is Al5Mg10(OH)31(SO4)2.xH2O.

Magaldrate

  • After ingestion of Novelta chewable tablet
  • The hydroxymagnesium is relatively rapidly converted to Magnesium ion
  • The negative charged layer situated between the positive charged layers that soaks up H+ ions
  • Rapid onset of action occurs
  • Aluminate converted to hydrated aluminium hydroxide
  • Reacts more slowly to give a sustained antacid effect
  • Prolonged acid neutralization occurs

    Simethicone

  • Acts in the stomach and intestine

  • Decreases the surface tension of gas bubbles

  • Enabling them to coalesce
  • Gas is freed and eliminated more easily
  • By belching or passing flatus

Dosage and Administration

1-4 tablets of Novelta chewable tablet, 20 minutes to 1 hour after meals and at bedtime, or as directed by physician.

To See Documentary on Novelta Please follow these link: Novelta: A Novel Antacid